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abcam ab178846 Anti-Iba1 抗体 [E

PR16588]
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  • ¥3645.38 - 5725.71
  • Abcam
  • ab178846
  • 2026年03月06日
  • WB, Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P
  • Rabbit
  • Mouse, Rat, Human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海然其生物科技有限公司

    • 克隆性

      单克隆

    • 保质期

      1-2 weeks

    • 抗体英文名

      Anti-Iba1 antibody [EPR16588] - Microglia marker

    • 抗体名

      Anti-Iba1 抗体 [EPR16588]

    • 宿主

      Rabbit

    • 适应物种

      Mouse, Rat, Human

    • 免疫原

      The exact immunogen used to generate this antibody is proprietary information.

    • 亚型

      IgG

    • 形态

      Liquid

    • 应用范围

      WB, Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P

    • 保存条件

      -20℃~4℃

    • 浓度

      1.172 mg/mL

    • 规格

      40ul/100ul

    规格:40ul产品价格:¥3645.38
    规格:100ul产品价格:¥5725.71

    产品详情

     

    Anti-Iba1 antibody [EPR16588] (ab178846) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB.

    Anti-Iba1 antibody [EPR16588] (ab178846) was first used in a scientific publication in 2016 and has been cited over 439 times in peer reviewed journals. It's performance in IHC, Western Blot and Immunofluorescence in mouse and rat samples is trusted by the scientific community.

    Abcam's high quality manufacturing and validation processes ensure Anti-Iba1 antibody [EPR16588] (ab178846) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.

    Anti-Iba1 antibody [EPR16588] (ab178846) has 44 independent reviews from customers.

    Anti-Iba1 antibody [EPR16588] (ab178846) specifically detects Iba1 (UniProt ID: O70200; Molecular weight: 17kDa) and is sold in 100 µL and 1 mL selling sizes.

    Conjugation-ready, carrier free format available for antibody clone EPR16588 - ab220815.

    Antibody clone EPR16588 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, APC, Alexa Fluor® 750 (ab225260, ab225261, ab320071, ab321218).

    NEW: Explore our alternative host species for clone [EPR16588] : goat, chicken, rat. Iba1 (AIF1) is a marker for microglia, the brain's primary immune cells and is frequently used in Alzheimer's disease (AD) research. In AD brains, altered Iba1 expression indicates microglial activation and neuroinflammation. Researchers use Iba1 to assess microglial response and motility in AD models, making it essential for understanding the role of inflammation and immune response in Alzheimer's pathology.

    Patented technologyOur RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    What are the advantages of a recombinant monoclonal antibody?This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free batch production

    For more information, read more on recombinant antibodies.

    形式

    Liquid

    纯化工艺

    Affinity purification Protein A

    存储溶液

    Preservative: 0.01% Sodium azide

    Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

    运输条件

    Blue Ice

    推荐的短期储存时间

    1-2 weeks

    推荐的短期储存条件

    +4°C

    推荐的长期储存条件

    -20°C

    分装信息

    Upon delivery aliquot

    储存信息

    Avoid freeze / thaw cycle

    靶点信息

    Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

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    图标文献和实验
    该产品被引用文献

    Microbiome 13:202 | PubMed 41063317

    2025

    Alternate day fasting alleviates neuroinflammation in diabetic mice by regulating δ-valerobetaine-carnitine-microglia axis via enrichment of Akkermansia muciniphila.

     

    Applications

    Unspecified application

    Species

    Unspecified reactive species

    Kaiyan Gong, Shuhui Zhang, Yangjie Pan, Qingpeng Cai, Mengjun Wu, Xiaoli Yin, Jiahui Ma, Hao Ji, Zhen Wang, Wenjun Wu, Hong Zheng

    Alzheimer's research & therapy 17:221 | PubMed 41057930

    2025

    Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology.

    out

    Applications

    Unspecified application

    Species

    Unspecified reactive species

    Raphaelle Caillierez, Clémence Leboullenger, Sarah Leclercq, Mélanie Besegher, Séverine Bégard, Florent Auger, Claude-Alain Maurage, Bertrand Accart, Justine Mortelecque, Elian Dupré, Clément Danis, Isabelle Landrieu, Luc Buée, Morvane Colin

    Cell death discovery 11:443 | PubMed 41053028

    2025

    A knock-in mouse model for GABRG2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.

    Applications

    Unspecified application

    Species

    Unspecified reactive species

    Dingding Shen, Jiali Wan, Xin Zhang, Jiahui Sui, Longwu Zhan, Yuqin Zheng, Yaohui Ni, Qi Zhang

    相关实验
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    • 【求助】甲基化抗体的选择

      在做对小鼠成纤维细胞的整个基因组的甲基化水平检测,我是想要关于免疫化学法中提及的关于anti-m5C的一抗和荧光标记的二抗的选择。我不知道怎么选择抗体。希望有这方面经验的专家或者有文献的前辈给我发一下吧。非常感谢。很急!!!!还要谢谢前面那位前辈。非常感谢。 藤崽 你说的是全基因组甲基化抗体吧,就是抗5-methyl cytosine的抗体,很多公司都有的,你查一下,我们用的是abcam公司的,四千左右,二抗就是普通的国产就行了

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    abcam ab178846 Anti-Iba1 抗体 [EPR16588]
    ¥3645.38 - 5725.71