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- BML-GR302-0010
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- 2026年03月04日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
少量现货
- 英文名：
Chromomycin A3
- CAS号：
7059-24-7
- 保质期：
As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
- 供应商：
欣博盛生物
- 保存条件：
-20°C
- 规格：
10 mg
Chromomycin A3产品货号BML-GR302，由ENZO公司研发生产，欣博盛生物是ENZO公司授权一级代理商，如需购买ENZO公司产品，技术问题，请联系欣博盛生物。热销品常备现货~
Transcription inhibitor
Chromomycin A3 is a GC-specific DNA ligand which inhibits transcription. It may be used as a fluorescent DNA stain. Antibiotic. Cell permeable fluorescent dye that cann be used with Bisbenzimide H33258 to distinguish chromosomes by their total DNA concentration and their DNA base composition. Does not intercalate. Ex(max): 445nm; Em(max): 575nm
Product Details
Appearance
Yellow solid.
CAS
7059-24-7
Couple Target
DNA
Couple Type
Ligand
Formula
C57H82O26
MW
1183.3
Purity
≥98% (TLC)
Solubility
Soluble in 100% ethanol, DMSO or ethyl acetate (10mg/ml)
Source
Isolated from Streptomyces griseus
Handling & Storage
Use/Stability
As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Handling
Protect from light.
Long Term Storage
-20°C
Shipping
Ambient Temperature
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文献和实验- Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells: S. Wong, et al.; Biochem. Pharmacol. 47, 827 (1994), Abstract
- Selective accumulation of diamidino yellow and chromomycin A3 by retinal glial cells: C.-J. Jeon & R.H. Masland; J. Histochem. Cytochem. 41, 1651 (1993), Abstract
- Specific staining of DNA with the fluorescent antibiotics, mithramycin, chromomycin, and olivomycin: H.A. Crissman & R.A. Tobey; Methods. Cell Biol. 33, 97 (1990), Abstract
- Chromomycin A3 and its derivatives: K. Mizuno; J. Antibiot. 16, 22 (1963)
Bivariate Chromosome Analysis Using a Commercial Flow Cytometer
The bivariate analysis of human chromosomes in flow using the fluorochromes Hoechst 33258 (with specificity for AT-rich DNA) and Chromomycin A3 (with specificity for GC-rich DNA) was first described by Gray et al. in 1979 (1 ). Chromosomes
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