- ￥1664.40 - 6796.30
- Enzo
- BML-NS105-0025
- 美国
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
少量现货
- 英文名：
Clozapine N-oxide
- 保质期：
见包装说明
- CAS号：
34233-69-7
- 供应商：
欣博盛生物
- 保存条件：
Ambient Temperature
- 规格：
25 mg/5 mg
| 规格： | 25 mg | 产品价格： | ￥6796.3 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1664.4 |
Clozapine N-oxide产品货号BML-NS105-0025，由ENZO公司研发生产，欣博盛生物是ENZO公司授权一级代理商，如需购买ENZO公司产品，技术问题，请联系欣博盛生物。热销品常备现货~
Major metabolite of clozapine
High purity
Active in vitroand in vivo
Possesses little-to-no activity at 5-HT receptors
Clozapine N-oxide (CNO) is a major metabolite of clozapine (Prod. No. BML-D107). CNO activates designer receptors exclusively activated by designer drugs (DREADDs) that are derived from human muscarinic acetylcholine receptors (M1-5D receptors).
Clozapine is an antipsychotic medication used in the treatment of schizophrenia, and is also sometimes used off-label for the treatment of bipolar disorder and borderline personality disorder. It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
Product Details
Alternative Name
CNO
Appearance
Yellow solid.
CAS
34233-69-7
Formula
C18H19ClN4O
Formulation
Contains 1 equivalent of methanol.
MW
342.8
Purity
≥99% (HPLC)
Solubility
Soluble in water (5mg/ml).
Source
Synthetic.
Handling & Storage
Use/Stability
As indicated on product label or CoA when stored as recommended.
Long Term Storage
Ambient
Shipping
Ambient Temperature
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- Development of activity-based anorexia requires PKC-d neurons in two central extended amygdala nuclei: W.I. Schnapp, et al.; Cell Rep. 43, 113933 (2024), Abstract
- Stimulus-Induced Activation of the Glycoprotein Hormone α-Subunit Promoter in Human Placental Choriocarcinoma Cells: Major role of a Tandem cAMP Response Element: L. Bürvenich, et al.; Curr. Issues Mol. Biol. 46, 3218 (2024), Abstract
- Circulating extracellular microRNAs in the blood promote sociability in mice: Dohi, E., Matoba, K., et al.; bioRxiv , (2024)
- Feedforward inhibition of stress by brainstem neuropeptide Y neurons: Zhang, Y., Shen, J., et al.; Nat. Commun. 15, 7603 (2024), Abstract
- Overactivation of prefrontal astrocytes impairs cognition through the metabolic pathway of central kynurenines: Beilmann, V., Furrer, J., et al.; bioRxiv , (2024)
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- A hippocampo-cortical pathway detects changes in the validity of an action as a predictor of reward.: Piquet, R., Faugère, A., et al.; Curr. Biol. 34, 24 (2024), Abstract
- APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors.: Dunot, J., Moreno, S., et al.; Neuron 112, 2708 (2024), Abstract
- D2-expressing neurons of the anterior paraventricular nucleus of the thalamus modulate learned aversive and safety salience: Miranda, M., Karam, E., et al.; bioRxiv , (2024)
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The Hypoxic Rat Model for Obstetric Complications in Schizophrenia
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