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北京柏瑞图科技有限公司
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文献和实验Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
Tumor suppressor proteins, like most proteins, require interacting with other proteins in the cell to function properly. These interacting proteins may be regulators or substrates of this tumor suppressor protein. A tumor suppressor protein
Molecular Detection of Smad2/Smad4 Alterations in Colorectal Tumors
, cell adhesion and cell death. The recent discovery of the SMAD family of signal transducer proteins as mediators of TGF-β relaying signals from cell membrane to nucleus has revolutionized the understanding of the molecular basis of these processes
Prediction of Interacting Protein Residues Using Sequence and Structure Data
Identifying hotspots responsible for protein interactions with other macromolecules or drugs provides insight into functional aspects of the protein network, and is a pivotal task in systems biology and drug discovery. Here, we present
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