Tumor Microenvironment-SignArr

The Tissue Microenvironment as an Epigenetic Tumor Modifier

, while tumors of similar grade can experience extended periods of dormancy (3 –5 ). Tumor metastasis and drug responsiveness are also just as difficult to predict (6 –8 ). This behavioral variability despite similarity in tumor phenotype demonstrates

Targeting the Tumor Microenvironment Using Photodynamic Therapy Combined with Inhibitors of Cyclooxygenase-2 or Vascular Endothelial Growth Factor

components of the tumor microenvironment. This indirect action of PDT leads to inflammatory and proangiogenic responses and modulates treatment effectiveness. Preclinical studies designed to determine how PDT modulates the tumor microenvironment use murine

Development and Activities of the BR96-Doxorubicin Immunoconjugate

have also been obtained when a MAb reacting with a differentiation antigen expressed on colorectal carcinomas was given to patients who were at high risk of tumor recurrence following primary surgery (5 ).