DIETHYL MALONATE FOR SYNTHESIS

Synthesis of Triazole‐Nucleoside Phosphoramidites and Their Use in Solid‐Phase Oligonucleotide Synthesis

oligonucleotides are macromolecules that have one or more triazole units that are acting as a backbone mimic. Triazoles within the backbone have been used within oligonucleotides for a variety of applications. This unit describes the preparation and synthesis

Synthesis, Characterization, and Application of Substituted Pyrazolopyrimidine Nucleosides

introduction of amino linkers into internal positions of synthetic DNA strands. Synthesis of suitably protected AP?PPA and AP?PPG phosphoramidites are described. The stepwise alkynylation, hydrogenation, selective protection, and phosphoramidite synthesis

Methoxyoxalamido Chemistry in the Synthesis of Tethered Phosphoramidites and Functionalized Oligonucleotides

Protocol 1: Preparation of Phosphoramidites Tethered with Multiple Linkers Basic Protocol 2: Synthesis, Deprotection, and Purification of Oligonucleotides Derivatized with Tethered Phosphoramidites Commentary