- ￥413
- Merck
- 美国
- 8.18663.1000
- 2026年02月12日
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文献和实验to replace combinattons of leucme coupled with valine in pepttde sequences. The preparation described is the final method developed, after many early less successful attempts. The synthesis mvolves (Fig. 1 ) the coupling of 1-bromo-5-methyl-2-hexene 3 and N
Synthesis of 2-O-Alkyloligoribonucleotides
2′-O -Alkyloligoribonucleotides possess properties that render them ideally suited for studying RNA processing and for the affinity chromatography of RNA-protein complexes. Particularly useful compounds are those in which alkyl is methyl (1 –
Synthesis and Purification of Phosphorodithioate DNA
3 ). These modifications, whereby a single nonbridging oxygen atom is replaced with either a methyl group or sulfur atom, generate certain very desirable oligomer characteristics (4 –7 ), such as resistance toward nucleases, retention of the ability to form duplexes
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