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Recombinant Human TGFBR2/TGF-b

eta receptor type-2
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  • ¥1200 - 3520
  • 近岸蛋白(Novoprotein)已认证
  • CC10
  • 中国
  • 2026年01月30日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      Recombinant Human TGFBR2/TGF-beta receptor type-2

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:询价
    规格:1mg产品价格:询价

    Recombinant Human TGFBR2/TGF-beta receptor type-2  (CC10)

     

    产品说明(Description)

    Recombinant Human Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus. 

    Accession #: P37173

    Known as: TGF-beta receptor type-2; TGF-beta type II receptor;TGFBR2; Transforming growth factor-beta receptor type II

     

    制剂(Formulation)

    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH 7.4.

     

    质量控制(Quality Control) 

    Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

    Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

     

    复溶(Reconstitution)

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in distilled water.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

     

    保存(Storage)

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

     

    背景(Background)

    TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.

     

    电泳(SDS-PAGE)

     

    FOR RESEARCH USE ONLY

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