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- 近岸蛋白(Novoprotein)
- 中国
- C172
- 2026年01月30日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human SENP8/Sentrin-specific protease 8
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥240.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥560.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human SENP8/Sentrin-specific protease 8 (C172)
产品说明(Description)
Recombinant Human Sentrin-Specific Protease 8 is produced by our E.coli expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the N-terminus.
Accession #: Q96LD8
Known as: Sentrin-Specific Protease 8; Deneddylase-1; NEDD8-Specific Protease 1; Protease Cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2
制剂（Formulation）
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输（Shipping）
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存（Storage）
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景（Background）
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
电泳(SDS-PAGE)
参考文献(References)
Vanadium-protein complex inhibits human adipocyte differentiation through the activation of β-catenin and LKB1/AMPK signaling pathway[J]. Shuang Zhang. et al. PLOS ONE. 2020.
Synthesis, characterization, antioxidant and anti‐diabetic activities of a novel protein–vanadium complex[J]. Shuang Zhang. et al. Applied Organometallic Chemistry. 2019.
FOR RESEARCH USE ONLY
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文献和实验Synthesis and Assay of Recombinant Adenovirus Protease
fragment of capsid protein pVI. This chapter describes the synthesis, purification, activation, and assay of recombinant human Ad type adenain.
(8 –11 ). The substrate specificity of the enzyme is (M,I,L)XGG-X or (M,I,L)XGX-G (12 ). Alkylating agents and E64 inhibit the protease and virus infection as expected (13 ). Specific inhibitors are not yet available. To date, 17 protease genes
High Throughput Production of Recombinant Human Proteins for Crystallography
, to be applied based on specific knowledge of protein families or when the core protocol is unsatisfactory. This scheme has been applied to more than 550 human proteins (>10,000 constructs) and has resulted in the deposition of 112 unique structures
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