- ￥840 - 2520
- 近岸蛋白(Novoprotein)
- 中国
- CJ20
- 2026年02月10日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human KLKB1/Plasma kallikrein
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥840.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2520.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human KLKB1/Plasma kallikrein (CJ20)
产品说明(Description)
Recombinant Human Plasma kallikrein is produced by our Mammalian expression system and the target gene encoding Gly20-Ala638 is expressed with a 6His tag at the C-terminus.
Accession #: P03952
Known as: Plasma kallikrein;Fletcher factor;Kininogenin;Plasma prekallikrein;KLKB1;KLK3
制剂（Formulation）
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输(Shipping)
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景（Background）
KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
电泳(SDS-PAGE)
参考文献（References）
Plasma kallikrein cleaves and inactivates apelin-17: Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agents[J]. ConradFischer. et al. European Journal of Medicinal Chemistry. 2019.
FOR RESEARCH USE ONLY
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