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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Recombinant Rhesus Macaque IFNAR1
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥840.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2520.0 |
| 规格: | 500ug | 产品价格: | 询价 |
| 规格: | 1mg | 产品价格: | 询价 |
Recombinant Rhesus Macaque IFNAR1 (C-6His) (CB21)
产品说明(Description)
Recombinant Rhesus macaque Interferon alpha/beta receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala25-Lys437 is expressed with a 6His tag at the C-terminus.
Accession #: XP_005548864.1
Known as: alpha-type antiviral protein; AVP; beta-type antiviral protein; CRF2-1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC; IFN-alpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-bR1; IFN-R-1
制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景(Background)
Interferon-alpha/beta receptor 1 (IFN- alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY
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