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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
负80℃至负20℃
- 英文名:
ADP-Ribosylation Factor6, ARF6(2-13)
- 供应商:
Bioyears
- 规格:
10mg
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文献和实验Preparation of Myristoylated Arf1 and Arf6 Proteins
ADP-ribosylation factor (Arf) proteins were first identified as cofactors for cholera toxin-catalyzed ADP-ribosylation of the heterotrimeric G-protein Gs. Subsequent cloning led to the discovery that Arfs were part of a group of GTP-binding
Arf6 and its Role in Cytoskeletal Modulation
4, and 5, and Class III Arfs have only one member-Arf6 (1 ). All Arf proteins have been shown to share a number of biochemical properties in vitro including: serving as cofactors in the ADP-ribosylation of Gs-alpha subunits induced by cholera toxin, activating
cells. The catalytic domain of diphtheria toxin catalyzes the NAD+ -dependent ADP-ribosylation of the diphthamide residue in elongation factor 2, resulting in inhibition of protein synthesis (20 ,21 ). As the delivery of a single molecule
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