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文献和实验Culture of Human Pancreatic Islet Cells
, which are mainly located in the center of the islet, are the insulin-producing �;β-cells In the periphery, α-cells and δ-cells synthesizing glucagon and somatostatin, respectively, are found. Finally, a small number of cells containing pancreatic polypeptide (PP
Isolation of Islets of Langerhans from Rodent Pancreas
Pancreatic β-cells, responsible for the synthesis and secretion of insulin in response to a glucose challenge, are located in the islets of Langerhans. Islets are comprised of a heterogeneous population of endocrine cells, including insulin
Y Receptors Characterized by RT-PCR: Distribution in Rat Intestine
, they have a very low affinity for pancreatic polypeptide (PP). They are exclusively present in proliferative crypt cells and appear to be quenched when epithelial cells migrate onto the villi, where they stop to divide and differentiate
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