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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human YAP (Phospho Ser127) protein
- 形态:
liquid
- 克隆性:
单克隆
- 保质期:
见COA
- 库存:
大量
- 供应商:
北京辰辉创聚生物技术有限公司
- 应用范围:
ELISA, IP, IF, IHC, WB
- 靶点:
YAP (Phospho Ser127)
- 抗体英文名:
Anti-YAP (Phospho Ser127) Monoclonal Antibody
- 抗体名:
抗YAP (Phospho Ser127)单抗
- 规格:
100ul; 500ul; 1ml

| 产品信息
品名:NebuSelect™ Anti-YAP (Phospho Ser127) Monoclonal Antibody
别名:YAP1, YAP65, Yorkie homolog, 65 kDa Yes-associated protein, YAP65
货号:NBAB-191571
品牌:Nebulabio
规格:100ul; 500ul; 1ml
| 产品描述
NebuSelect™ Anti-YAP (Phospho Ser127) Monoclonal Antibody (Cat# NBAB-191571) was produced in rabbits immunized with recombinant Human YAP (Phospho Ser127) protein, and it reacts with Human, Mouse, Rat. This antibody is validated for ELISA, IP, IF, IHC, WB.
| 产品属性
Product Category:Rabbit MAb
Reactivity:Human, Mouse, Rat
Specificity:Human YAP (Phospho Ser127)
Immunogen:Recombinant Human YAP (Phospho Ser127) protein
Isotype:Monoclonal Rabbit IgG
Purification:Protein A & Protein G Affinity Purification
Buffer:0.2 μm filtered solution in PBS, pH7.4, containing 0.09% Sodium azide, 50% glycerol.
Conjugate:Unconjugated
Applications:ELISA, IP, IF, IHC, WB
Dilution:ELISA 1:2000~1:10000; IP:1:50~1:500 IF 1:50~1:500; IHC-P 1:50~1:500; WB: 1:1000~1:5000
Storage:This liquid antibody can be stored at 2℃-8℃ for at least two weeks. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or antibody diluent, the antibody is stable for at least two weeks at 2-4℃.
For Research Use Only!
To get more information, please contact us freely.
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
STM:广州医科大学刘铭/谢茂彬合作发现肝细胞癌的新潜在治疗靶点 Claudin 6
显示,CLDN6 可以稳定 YAP1,促进其核转位,从而活化 Hippo 通路。 IP 结果显示 CLDN6 与 YAP1 竞争性结合 TJP2 鉴于 CLDN6 是多次跨膜蛋白,但其不具有(或尚未发现?)配体结合结构域,难以设计小分子药物;而如果使用单抗的话,由于肝细胞癌具有复杂的微环境, T 细胞难以发挥足够的抗体依赖细胞毒性(ADCC)效应杀伤癌细胞。因此,作者设计了靶向 CLDN6 的抗体偶联药物(Antibody-Drug Conjugate, ADC),将细胞毒性药物 DM1 和 CLDN6 抗体
largely independent of the surrounding amino-acid sequence. The antibody is phospho-specific but does not cross-react with phospho-serine-containing sequences. The anti-phosphothreonine monoclonal antibody is labeled with Eu3+ Cryptate by Cisbio
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