抗GSK3 α/β (Phospho Tyr216/Tyr2
79)单抗 | Anti-GSK3 α/β (Phospho Tyr216/Tyr279) Monoclonal Antibody- 询价
- Nebulabio
- 中国
- NBAB-191561
- 2026年01月05日
- ELISA, WB
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human GSK3 α/β (Phospho Tyr216/Tyr279)protein
- 形态：
liquid
- 克隆性：
单克隆
- 保质期：
见COA
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 应用范围：
ELISA, WB
- 靶点：
GSK3 α/β (Phospho Tyr216/Tyr279)
- 抗体英文名：
Anti-GSK3 α/β (Phospho Tyr216/Tyr279) Monoclonal Antibody
- 抗体名：
抗GSK3 α/β (Phospho Tyr216/Tyr279)单抗
- 规格：
100ul; 500ul; 1ml
| 产品信息
品名：NebuSelect™ Anti-GSK3 α/β (Phospho Tyr216/Tyr279) Monoclonal Antibody
别名：GSK3A, Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta, Serine/threonine-protein kinase GSK3B
货号：NBAB-191561
品牌：Nebulabio
规格：100ul; 500ul; 1ml
| 产品描述
NebuSelect™ Anti-GSK3 α/β (Phospho Tyr216/Tyr279) Monoclonal Antibody (Cat# NBAB-191561) was produced in rabbits immunized with recombinant Human GSK3 α/β (Phospho Tyr216/Tyr279)protein, and it reacts with Human, Mouse, Rat. This antibody is validated for ELISA, WB.
| 产品属性
Product Category：Rabbit MAb
Reactivity：Human, Mouse, Rat
Specificity：Human GSK3 α/β (Phospho Tyr216/Tyr279)
Immunogen：Recombinant Human GSK3 α/β (Phospho Tyr216/Tyr279)protein
Isotype：Monoclonal Rabbit IgG
Purification：Protein A & Protein G Affinity Purification
Buffer：0.2 μm filtered solution in PBS, pH7.4, containing 0.09% Sodium azide, 50% glycerol.
Conjugate：Unconjugated
Applications：ELISA, WB
Dilution：ELISA 1:2000～1:10000; WB: 1:1000～1:5000
Storage：This liquid antibody can be stored at 2℃-8℃ for at least two weeks. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or antibody diluent, the antibody is stable for at least two weeks at 2-4℃.
For Research Use Only!
To get more information, please contact us freely.
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文献和实验) is accompanied with or inactivates the GSK activity. However, it is still not conclusive what the role of Tyr phosphorylation (Y216 fro beta, Y279 for alpha) on GSK activity is. One reference is a review paper published in Cell in 2001, you may take a quick
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
loop of the kinase domain (Tyr279 in GSK3a, andTyr216 in GSK3b), which is absolutely required for kinase activity. Thirdly, phosphorylation of GSK3 at a conserved N-terminalserine residue inhibits its kinase activity. This phosphoserine actsas
. Fig. 5.1. Inhibition of GSK-3 activity. A Depletion of both GSK-3α and GSK-3β is required for a decrease of β-catenin phosphorylationat Ser33/37. Panc04.03 cells were transfected with shControl, shGSK-3α, and shGSK-3β vectors, as describedin
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