IL‑30, IL-27/IL-27-A, 重组蛋白,细胞因

Mouse IL-30 Protein (PRP1310)

产品名称：重组小鼠白介素-30（IL-30）蛋白
英文名称：Mouse IL-30 protein
货号：PRP1310

产品概述

重组小鼠白介素-30（IL-30）是一种无标签的高纯度细胞因子蛋白，来源于大肠杆菌表达系统。该产品经过严格质控，纯度经SDS-PAGE检测大于99%，适用于细胞培养及相关科学研究应用。IL-30作为IL-6/IL-12细胞因子家族的重要成员，在免疫调节和炎症反应中具有重要作用。

技术参数

• 种属来源：小鼠（Mouse）
• 蛋白序列：氨基酸序列源自重组小鼠IL-30（UniProt: Q8K3I6），对应片段 Phe29-Ser234
• 蛋白长度：206个氨基酸
• 预测分子量：24.9 kDa
• 表达宿主：大肠杆菌表达系统
• 纯度：＞99%（SDS-PAGE检测）
• 内毒素水平：＜1.0 EU/μg（LAL法测定）
• 产品形式：冻干粉，缓冲体系为20 mM Tris，150 mM NaCl，pH 7.4
• 活性状态：待进一步检测（Testing in Progress）

使用建议

• 复溶方法：推荐使用配套复溶缓冲液（Reconstitution Buffer）进行溶解，建议浓度不低于100 µg/mL，后续可根据实验需要进行稀释。
• 注意事项：使用前请离心，避免产品散失。
• 保存条件：冻干粉可在-20℃以下干燥环境中长期保存；复溶后可在4℃稳定保存2–7天，长期保存建议分装并存于-20℃以下，可添加0.1% HSA或BSA作为稳定剂。
• 运输条件：冰袋运输（蓝冰）

背景信息

IL-30是一种28 kDa分泌蛋白，属于IL-6/IL-12细胞因子家族。其在巨噬细胞和树突状细胞中表达，并在炎症刺激下上调表达。作为IL-27的一个亚基，IL-30与EBI3形成异源二聚体，通过IL-27Rα/gp130受体复合物传导信号，参与CD4+ T细胞、NK细胞等多种免疫细胞的调控，兼具促炎和抗炎双重功能。

基因ID：246779
别名：IL‑30, IL-27/IL-27-A

规格与价格

规格	价格（元）	货期
5 μg	588	现货，次日发货
20 μg	1498	现货，次日发货
100 μg	3198	现货，次日发货
1 mg	请咨询	请咨询

警告：本品仅供科研使用，不适用于人类或临床诊断。使用者应负责确保应用方式不侵犯任何专利权或法规要求。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Mouse IL-30 Protein (PRP1310)

Product Name: Recombinant Mouse Interleukin‑30 (IL‑30) Protein
English Name: Mouse IL‑30 protein
Catalog No.: PRP1310

Product Overview

The recombinant mouse interleukin‑30 (IL‑30) is a tag‑free, high‑purity cytokine protein produced in an Escherichia coli expression system. This product undergoes stringent quality control, with purity >99% as assessed by SDS‑PAGE, and is suitable for cell‑culture and related scientific research applications. IL‑30, an important member of the IL‑6/IL‑12 cytokine family, plays a pivotal role in immune regulation and inflammatory responses.

Technical Specifications

• Species Source: Mouse
• Protein Sequence: Amino‑acid sequence derived from recombinant mouse IL‑30 (UniProt: Q8K3I6), corresponding to the fragment Phe29‑Ser234
• Protein Length: 206 amino acids
• Theoretical Molecular Weight: 24.9 kDa
• Expression Host: Escherichia coli expression system
• Purity: >99% (SDS‑PAGE)
• Endotoxin Level: <1.0 EU/µg (LAL assay)
• Product Form: Lyophilized powder; buffer: 20 mM Tris, 150 mM NaCl, pH 7.4
• Activity Status: Testing in progress

Recommended Use

• Reconstitution Method: It is recommended to dissolve the lyophilized material with the supplied Reconstitution Buffer, at a concentration not lower than 100 µg/mL; subsequent dilutions can be made according to experimental needs.
• Precautions: Centrifuge before use to prevent product loss.
• Storage Conditions: Lyophilized powder may be stored long‑term in a dry environment at ≤ ‑20 °C; after reconstitution, the solution is stable at 4 °C for 2–7 days. For extended storage, aliquot and keep at ≤ ‑20 °C, optionally adding 0.1 % HSA or BSA as a stabilizer.
• Shipping Conditions: Shipped on dry ice (blue ice pack)

Background Information

IL‑30 is a 28 kDa secreted protein belonging to the IL‑6/IL‑12 cytokine family. It is expressed in macrophages and dendritic cells and is up‑regulated upon inflammatory stimulation. As one subunit of IL‑27, IL‑30 heterodimerizes with EBI3 to form a functional cytokine that signals through the IL‑27Rα/gp130 receptor complex, modulating the activity of CD4⁺ T cells, NK cells, and other immune cells, and exhibits both pro‑inflammatory and anti‑inflammatory functions.

Gene ID: 246779
Aliases: IL‑30, IL‑27/IL‑27‑A

Specifications and Pricing

Specification	Price (CNY)	Lead Time
5 µg	588	In stock, next‑day shipment
20 µg	1498	In stock, next‑day shipment
100 µg	3198	In stock, next‑day shipment
1 mg	Please inquire	Please inquire

Warning: This product is for research use only and is not intended for human or clinical diagnostic applications. Users are responsible for ensuring that their use does not infringe any patents or regulatory requirements.

Note: The above information may change due to product optimization or upgrades; please consult Yakoin Inc. for the most current details.