IL-6细胞因子,重组大鼠白细胞介素-6(IL-6),重组蛋

重组大鼠白细胞介素-6 (IL-6) 蛋白

产品货号: PRP1201

英文名称: Rat IL-6 Protein

本品为大肠杆菌表达的重组大鼠白细胞介素-6蛋白，提供高纯度、低内毒素的冻干粉制剂，专为细胞培养等生命科学研究领域设计。

产品特性

• 高纯度: 经SDS-PAGE验证，纯度 > 98 %。
• 低内毒素水平: 通过LAL法测定，每微克蛋白内毒素含量 < 0.1 EU，有效降低实验背景干扰。
• 无标签设计: 蛋白序列天然，避免了标签可能带来的功能干扰。
• 严格的质量控制: 确保产品批次间的一致性。

产品描述

白细胞介素-6 (IL-6) 是由IL-6基因编码的一种多效性细胞因子，兼具促炎和抗炎活性。它由T细胞和巨噬细胞等分泌，在免疫应答、细胞增殖与分化中扮演关键角色。本产品是通过基因重组技术在大肠杆菌中表达的大鼠源IL-6蛋白片段 (Fhe25-Thr211)，分子量约为20.6 kDa。

技术参数

• 种属来源: 大鼠 (Rattus norvegicus)
• 表达宿主: 大肠杆菌 (E.coli)
• 蛋白序列: 氨基酸序列来源于UniProt数据库登录号 P20607。
• 产品形式: 冻干粉，冻干缓冲液为无菌的20 mM Tris，250 mM NaCl，pH 8.0。

使用建议

• 复溶: 开盖前请先离心。推荐使用产品附带的复溶缓冲液进行复溶，初始浓度建议不低于100 µg/mL，后续可根据实验需求进行稀释。
• 保存: 冻干粉在-20°C条件下可稳定保存1年。复溶后于2-8°C可保存1周。若在含有载体蛋白（如0.1% BSA）的缓冲液中稀释并分装，于-20°C或-80°C可保存3-6个月，请避免反复冻融。

规格与价格

规格	价格 (人民币)	货期
5 µg	588	现货（次日发货）
20 µg	1498	现货（次日发货）
100 µg	4369	请咨询
1 mg	请咨询	请咨询

运输条件

本品采用蓝冰（冰袋）运输，以确保运输过程中的稳定性。

注意事项

警告: 本产品仅限于科研使用，不适用于人类或临床诊断。使用者应确保其应用不违反任何专利或许可证规定。对于因使用本产品可能导致的专利侵权或其他违规行为，本公司不承担任何责任。

基因ID: 24498 | 别名: BSF2, HGF, HSF, IL-6, Interleukin-6

蛋白质数据库链接: Il6 - Interleukin-6 - Rattus norvegicus (Rat) | UniProtKB | UniProt

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Rat Interleukin-6 (IL-6) Protein

Product Code: PRP1201

English Name: Rat IL-6 Protein

This product is a recombinant rat interleukin‑6 protein expressed in Escherichia coli, supplied as a high‑purity, low‑endotoxin lyophilized powder, specifically designed for cell‑culture and other life‑science research applications.

Product Features

• High purity: Confirmed by SDS‑PAGE with purity > 98%.
• Low endotoxin level: Determined by LAL assay; endotoxin content < 0.1 EU per µg protein, effectively reducing background interference.
• Tag‑free design: Native protein sequence, avoiding potential functional interference from affinity tags.
• Strict quality control: Ensures batch‑to‑batch consistency.

Product Description

Interleukin‑6 (IL‑6) is a pleiotropic cytokine encoded by the IL‑6 gene, exhibiting both pro‑inflammatory and anti‑inflammatory activities. It is secreted by T cells, macrophages, and other cells, playing a pivotal role in immune responses, cell proliferation, and differentiation. This product is a recombinant rat‑derived IL‑6 fragment (Phe25‑Thr211) expressed in E. coli, with an approximate molecular weight of 20.6 kDa.

Technical Specifications

• Species origin: Rat (Rattus norvegicus)
• Expression host: Escherichia coli (E. coli)
• Protein sequence: Amino‑acid sequence derived from UniProt entry P20607.
• Product format: Lyophilized powder; reconstitution buffer is sterile 20 mM Tris, 250 mM NaCl, pH 8.0.

Recommended Usage

• Reconstitution: Centrifuge before opening. It is recommended to use the supplied reconstitution buffer, targeting an initial concentration of ≥100 µg/mL; further dilution can be performed according to experimental needs.
• Storage: Lyophilized powder is stable at –20 °C for up to 1 year. After reconstitution, store at 2–8 °C for up to 1 week. When diluted in a buffer containing a carrier protein (e.g., 0.1 % BSA) and aliquoted, the sample can be kept at –20 °C or –80 °C for 3–6 months; avoid repeated freeze‑thaw cycles.

Specifications & Pricing

Specification	Price (CNY)	Lead Time
5 µg	588	In stock (next‑day shipment)
20 µg	1498	In stock (next‑day shipment)
100 µg	4369	Please inquire
1 mg	Please inquire	Please inquire

Shipping Conditions

The product is shipped on dry ice (ice packs) to maintain stability during transit.

Precautions

Warning: This product is for research use only and is not intended for human or clinical diagnostic applications. Users must ensure that their use does not infringe any patents or licence agreements. The company assumes no liability for any patent infringement or other violations arising from the use of this product.

Gene ID: 24498 | Aliases: BSF2, HGF, HSF, IL-6, Interleukin-6

Protein database link: Il6 - Interleukin-6 - Rattus norvegicus (Rat) | UniProtKB | UniProt

Note: The above information may change due to product optimization or other factors; please contact Yakoin for the latest details.