BMP-15 人源重组蛋白 细胞因子

Human BMP-15 Protein, His tag (BMP-15 人源重组蛋白)

货号：PRP1231 | 产品类型：细胞因子

Human BMP-15 Protein, His tag是一种由大肠杆菌表达系统重组生产的、高纯度人源骨形态发生蛋白15片段。该产品通过严格的质控流程，确保其高纯度与高稳定性，是进行卵泡发育、颗粒细胞功能及相关信号通路研究的可靠工具。

产品特性

• 高纯度：经SDS-PAGE检测，纯度 > 98%
• 低内毒素：LAL法检测，内毒素含量 < 0.1 EU/μg
• 明确分子量：预测分子量为34.1 kDa（含TrxA标签）
• 冻干形态：提供冻干粉剂型，便于运输与储存

产品描述

本产品为人源BMP-15（Bone Morphogenetic Protein 15）的重组蛋白片段，其氨基酸序列覆盖Gln268-Arg392区域（UniProt编号：O95972），并融合His标签与TrxA标签以提高其稳定性和可溶性。BMP-15属于TGF-β超家族配体，在卵泡发育过程中由卵母细胞特异性表达，对颗粒细胞增殖、糖酵解及胆固醇合成具有显著促进作用，是女性生殖生物学研究中的关键因子。

应用方向（研究用途）

• 颗粒细胞（Granulosa Cells）体外功能研究
• 卵母细胞-颗粒细胞互作机制分析
• BMP/SMAD信号通路激活实验
• 细胞增殖与代谢相关研究

使用说明

本品为冻干粉形式，建议使用配套复溶缓冲液（Reconstitution Buffer）复溶至浓度不低于100 µg/mL，后续可根据实验体系进行稀释。复溶后可在4℃短期保存，若需长期保存，请添加0.1% HSA或BSA作为载体蛋白，并分装存于-20℃以下，避免反复冻融。

保存与运输

• 保存条件：-20℃以下干燥环境
• 运输条件：冰袋（蓝冰）运输

规格与价格

规格	价格（元）	货期
5 μg	588	现货，次日发货
20 μg	1498	现货，次日发货
100 μg	4698	现货，次日发货
1 mg	请咨询	请咨询

注意：本品仅供科研使用，不适用于临床诊断、治疗或其他人体用途。

别名：BMP15, BMP-15, GDF-9B, ODG2, POF4, Bone morphogenetic protein 15, Growth/Differentiation Factor-9B

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Human BMP-15 Protein, His tag (BMP-15 Recombinant Human Protein)

Catalog No.: PRP1231 | Product Type: Cytokine

Human BMP-15 Protein, His tag is a high‑purity recombinant fragment of human Bone Morphogenetic Protein‑15 produced in an E. coli expression system. The product undergoes rigorous quality‑control procedures to ensure high purity and stability, providing a reliable tool for studies of folliculogenesis, granulosa‑cell function and associated signaling pathways.

Product Characteristics

• High Purity: SDS‑PAGE analysis, purity > 98%
• Low Endotoxin: LAL assay, endotoxin < 0.1 EU/µg
• Defined Molecular Weight: Predicted MW = 34.1 kDa (including TrxA tag)
• Lyophilized Form: Provided as a lyophilized powder for convenient shipping and storage

Product Description

This product is a recombinant fragment of human BMP‑15 (Bone Morphogenetic Protein 15) covering the Gln268‑Arg392 region (UniProt ID: O95972). It is fused with a His tag and a TrxA tag to enhance stability and solubility. BMP‑15 belongs to the TGF‑β superfamily of ligands and is oocyte‑specific during folliculogenesis, markedly promoting granulosa‑cell proliferation, glycolysis, and cholesterol synthesis, making it a pivotal factor in female reproductive biology research.

Applications (Research Use)

• In‑vitro functional studies of granulosa cells
• Analysis of oocyte‑granulosa cell interaction mechanisms
• BMP/SMAD signaling pathway activation assays
• Cell proliferation and metabolism–related investigations

Usage Instructions

The product is supplied as a lyophilized powder. Reconstitute with the provided Reconstitution Buffer to a concentration of at least 100 µg/mL, then dilute as required for your assay. The reconstituted solution can be stored short‑term at 4 °C. For long‑term storage, add 0.1 % HSA or BSA as a carrier protein, aliquot, and keep at ≤ ‑20 °C to avoid repeated freeze‑thaw cycles.

Storage and Shipping

• Storage Condition: Dry environment at ≤ ‑20 °C
• Shipping Condition: Transport on ice packs (blue ice)

Specifications and Pricing

Specification	Price (CNY)	Lead Time
5 µg	588	In stock, next‑day shipment
20 µg	1498	In stock, next‑day shipment
100 µg	4698	In stock, next‑day shipment
1 mg	Please inquire	Please inquire

Note: This product is for research use only and is not intended for clinical diagnosis, therapy, or any other human application.

Synonyms: BMP15, BMP-15, GDF-9B, ODG2, POF4, Bone Morphogenetic Protein 15, Growth/Differentiation Factor‑9B

Note: The above information is subject to change due to product optimization or upgrades; please contact Yakoin Co. for the most current details.