6194赛默飞实验室冰箱配件Thermo Fisher DU

Uridine 2′‐Carbamates: Facile Tools for Oligonucleotide 2′‐Functionalization

upon hybridization to a complementary RNA (but not DNA). Keywords: nucleoside; uridine carbamate; oligonucleotide modification; duplex stability; pyrene; fluorescence        

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

) and Cs2 CO3 under a nitrogen atmosphere. Conversion to the O 6 ?(benzotriazol?1?yl) ethers occurs within about 10 min for inosine, and within about 60 min for guanosine and 2??deoxyguanosine. Then, for reaction with alcohols, the reaction mixture

Time‐Dependent Thermocontrol of the Hydrophilic and Lipophilic Properties of DNA Oligonucleotide Prodrugs

and Their Conversion to Phosphorothioate Diesters Under Thermolytic Conditions Basic Protocol 6: Automated Solid‐Phase Synthesis of a Heat‐Sensitive DNA Prodrug Model and Its Selective Thermolytic Deprotection Commentary