- 询价
- BIO-RAD
- MCA740SBV710
- 2025年12月11日
- F
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1
- 形态：
Purified IgG conjugated to StarBright Violet 710 - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
StarBright Violet 710
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
AK2
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
F
- 浓度：
For information on the concentration of our StarBright Dye conjugated reagents please visit our FAQ page.
- 抗体名：
CD42b antibody | AK2
- 规格：
100 Tests/0.5ml
Mouse anti Human CD42b antibody, clone AK2 recognizes the human CD42b cell surface antigen, also known as platelet glycoprotein GP1B.
CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.
CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.
储存信息
This product is shipped at ambient temperature.
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted.
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | Neat |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 5μl of the suggested working dilution to label 106 cells in 100μl. Best practices suggest a 5 minutes centrifugation at 6,000g prior to sample application.
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文献和实验该产品被引用文献
References for CD42b antibody
- Ward, C.M. & Berndt, M.C. (1995) Epitope and functional characterization of the CD42 (gpIb/IX) mAb panel.
Leucocyte Typing V. White Cell Differentiation Antigens. Volume Two. Oxford University Press, Oxford. - Burgess, J.K. et al. (1998) Quinine-dependent antibodies bind a restricted set of epitopes on the glycoprotein Ib-IX complex: characterization of the epitopes.
Blood. 92: 2366-73. - Burgess, J.K. et al. (2000) Rifampicin-dependent antibodies bind a similar or identical epitope to glycoprotein IX-specific quinine-dependent antibodies.
Blood. 95: 1988-92. - Jayo, A. et al. (2010) L718P mutation in the membrane-proximal cytoplasmic tail of beta 3 promotes abnormal alpha IIb beta 3 clustering and lipid microdomain coalescence, and associates with a thrombasthenia-like phenotype.
Haematologica. 95: 1158-66. - Lova, P. et al. (2004) Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.
J Biol Chem. 279: 25299-306. - Shen, Y. et al. (2000) Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex.
Blood. 95: 903-10. - Wright, S.D. et al. (1993) Double heterozygosity for mutations in the platelet glycoprotein IX gene in three siblings with Bernard-Soulier syndrome.
Blood. 81: 2339-47. - Nomura, S. et al. (1995) Significance of cytokines and CD68-positive microparticles in immune thrombocytopenic purpura.
Eur J Haematol. 55: 49-56.
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Mouse anti Human CD42b:StarBright Violet 710
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