Rat anti Mouse CD11b:StarBright UltraViolet 445
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Rat anti Mouse CD11b:StarBrigh

t UltraViolet 445
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  • 询价
  • BIO-RAD已认证
  • MCA711SBUV445
  • 2025年12月11日
  • F
  • Mouse
  • 详细信息
  • 文献和实验
  • 技术资料
  • 免疫原

    Thioglycollate-elicited peritoneal macrophages (TPM)

  • 亚型

    IgG2b

  • 形态

    Purified IgG conjugated to StarBright UltraViolet 445 - liquid

  • 克隆性

    Monoclonal Antibody

  • 标记物

    StarBright UltraViolet 445

  • 适应物种

    Mouse

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    5C6

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 应用范围

    F

  • 浓度

    For information on the concentration of our StarBright Dye conjugated reagents please visit our FAQ page.

  • 抗体名

    CD11b antibody | 5C6

  • 规格

    100 Tests/0.5ml

Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.

Rat anti Mouse CD11b antibody, clone 5C6 immunoprecipitates a heterodimer of ~165 and ~95 kDa. This clone also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.


储存信息

This product is shipped at ambient temperature.
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Flow Cytometry

Use 5ul of the suggested working dilution to label 106 cells in 100ul. Best practices suggest a 5 minutes centrifugation at 6,000g prior to sample application.



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图标文献和实验
该产品被引用文献

References for CD11b antibody

  1. Rosen, H. and Gordon, S. (1987) Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.
    J Exp Med. 166: 1685-701.
  2. Rosen, H. et al. (1989) Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo.
    J Exp Med. 169: 535-48.
  3. Serafini, B. et al. (2000) Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis.
    Am J Pathol. 157: 1991-2002.
  4. Platt, N. et al. (2000) Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal.
    J Immunol. 164: 4861-7.
  5. Carenini, S. et al. (2001) The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0.
    J Cell Biol. 152: 301-8.
  6. Engwerda, C.R. et al. (2002) Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria.
    J Exp Med. 195: 1371-7.
  7. Mittal, A. et al. (2003) CD11b+ cells are the major source of oxidative stress in UV radiation-irradiated skin: possible role in photoaging and photocarcinogenesis.
    Photochem Photobiol. 77 (3): 259-64.
  8. Lesnik, P. et al. (2003) Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.
    J Clin Invest. 111: 333-40.
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Rat anti Mouse CD11b:StarBright UltraViolet 445
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