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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TIA1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1100
- 标记物:
Vio B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
TIA1 Antibody, anti-human, REAdye_lease™
- 抗体名:
TIA1 Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of TIA1+ cellsClone REAL1100 is an antibody fragment derived from the full TIA1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1100 recognizes human TIA1 (TIA-1), a cytotoxic granule-associated protein that is a member of a RNA-binding protein family. It regulates transcription and RNA translation, acts in the nucleus to regulate splicing and is associated with apoptosis. TIA1 is expressed in cytotoxic lymphocyte (CTL) target cells, in which it induces DNA fragmentation. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Kedersha, N. L. et al. (1999) RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J. Cell Biol. 147 (7): 1431–1442. | Izquierdo, J.M. et al. (2005) Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition. Mol. Cell 19 (4): 475–484. | Lee, D. Y. et al. (2020) ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics. Neurochem. Res. 45 (12): 2884–2893.
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TIA1 Antibody, anti-human, Vio® B515, REAdye_lease™, 200 µL
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