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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD151
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA265
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:11
- 抗体英文名:
CD151 Antibody, anti-human, REAfinity™
- 抗体名:
CD151 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 1 mL
Identification and enumeration of CD151+ cells by flow cytometryClone REA265 recognizes the CD151 antigen, a 29 kDa cell surface glycoprotein, which is also known as platelet-endothelial tetraspan antigen 3 (PETA-3) or tetraspanin-24 (Tspan-24). Like other tetraspanin family members, CD151 contains four hydrophobic transmembrane domains, two short cytoplasmic tails, and one small and one large extracellular loop. CD151 is expressed by many different cell types such as platelets, immature hematopoietic cells, megakaryocytes, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, as well as epithelial cells. It complexes with integrins and other transmembrane 4 superfamily proteins and is involved in cellular processes including cell adhesion and regulates integrin trafficking and function. CD151 enhances cell motility, invasion, and metastasis of tumor cells. | Additional information: Clone REA265 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Karamatic, C. V. et al. (2004) CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 104 (8): 2217–2223. | Kohno, M. et al. (2002) CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int. J. Cancer 97 (3): 336–343. | Chernousov, M. A. et al. (2013) Tetraspanins are involved in Schwann cell-axon interaction. J. Neurosci. Res. 91 (11): 1419–1428.
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CD151 Antibody, anti-human, Biotin, REAfinity™, 100 tests in 1 mL
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