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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
PSMD1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1227
- 标记物:
Vio R667
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
PSMD1 Antibody, anti-human, REAdye_lease™
- 抗体名:
PSMD1 Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of PSMD1+ cellsClone REAL1227 is an antibody fragment derived from the full PSMD1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1227 recognizes PSMD1 (26S proteasome non-ATPase regulatory subunit 1), also as known as 26S Proteasome Regulatory Subunit Rpn2, a component of the 26S proteasome and multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. PSMD1 is invoved in homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and in removing proteins whose functions are no longer required. It participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Gadhave, K. et al. (2016) The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease. J. Cell. Mol. Med. 20 (7): 1392–1407. | Bencomo-Alvarez, A. E. et al. (2021) Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3), play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B. Oncogene 40 (15): 2697–2710. | Rubio, A. J. et al. (2021) 26S Proteasome Non-ATPase Regulatory Subunits 1 (PSMD1) and 3 (PSMD3) as Putative Targets for Cancer Prognosis and Therapy. Cells 10 (9): 2390 doi.
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PSMD1 Antibody, anti-human, Vio® R667, REAdye_lease™, 200 µL
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