- 询价
- Miltenyi Biotec
- 德国
- 130-130-561
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IL-22
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA466
- 标记物：
APC-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:50
- 抗体英文名：
IL-22 Antibody, anti-human, REAfinity™
- 抗体名：
IL-22 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of IL-22+ cells by flow cytometryClone REA466 recognizes the human interleukin-22 (IL-22) antigen, a secreted molecule which belongs to the IL-10 family of cytokines. IL-22 is produced by immune cells, including T helper cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in particular epithelial cells, keratinocytes, and hepatocytes. It plays an important role in host defense at mucosal surfaces as well as in tissue repair. Although IL-22 is beneficial to the host in many infectious and inflammatory disorders, depending on the target tissue it can be pathogenic due to its inherent pro-inflammatory properties, which are further enhanced when IL-22 is released together with other pro-inflammatory cytokines, in particular IL-17. | Additional information: Clone REA466 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Dumoutier, L. et al. (2000) Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10144–10149. | Rutz, S. et al. (2013) IL-22, not simply a Tʜ17 cytokine. Immunol. Rev. 275 (1): 116–132. | Xie, M. H. et al. (2013) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275 (40): 31335–31339.
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IL-22 Antibody, anti-human, APC-Vio® 770, REAfinity™, 100 tests in 200 µL
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