- 询价
- Miltenyi Biotec
- 德国
- 130-124-785
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
PI3K p85 α
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL589
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
PI3K p85 α Antibody, anti-human, REAdye_lease™
- 抗体名：
PI3K p85 α Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of PI3K p85 α+ cellsClone REAL589 is an antibody fragment derived from the full PI3K p85 alpha antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL589 recognizes the human Phosphoinositide 3-kinase (PI3K), also known as phosphatidylinositol 3-kinase which belongs to the family of related intracellular signal transducer enzymes. PI3Ks are involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Mutations in the gene promote the development of diseases such as allergies, heart diseases, inflammatory processes or cancer. The superfamily of PI3 Kinases consists of several enzymes, which are structurally closely related. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
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文献和实验该产品被引用文献
Thorpe, L. M. et al. (2015) PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting. Nat. Rev. Cancer 15 (1): 7–24. | Kaneda, M. M. et al. (2016) PI3Kγ is a molecular switch that controls immune suppression. Nature 539 (7629): 437–442. | Rodgers, S. J. et al. (2017) Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases. Biosci. Rep. 37 (1): –BSR2016043.
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PI3K p85 α Antibody, anti-human, APC, REAdye_lease™, 200 µL
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