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Caveolin-1 Antibody, anti-huma

n, PE, REAdye_lease™, 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-129-282
  • 2025年12月09日
  • MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • cell line
  • human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Caveolin-1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REAL686

    • 标记物

      PE

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      cell line

    • 应用范围

      MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 抗体英文名

      Caveolin-1 Antibody, anti-human, REAdye_lease™

    • 抗体名

      Caveolin-1 Antibody, anti-human, REAdye_lease™

    • 规格

      200 µL

    Detection of Caveolin-1+ cellsClone REAL686 is an antibody fragment derived from the full Caveolin-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL686 recognizes the Caveolin-1 protein, a main component of the caveolae plasma membranes found in most cell types. It links integrin subunits to the tyrosine kinase FYN and promots cell cycle progression. The coding CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. Caveolin 1 has been shown to interact with a range of molecules via caveolin-binding motifs (CBM) through a caveolin-scaffolding domain (CSD) within caveolin-1 molecule. High Caveolin-1 levels were correlated with tumor progression, invasion and metastasis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |

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    图标文献和实验
    该产品被引用文献
    Razani, B. et al. (2001) Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor". J. Biol. Chem. 276 (9): 6727–6738. | Ketteler, J. et al. (2018) Caveolin-1, cancer and therapy resistance. Int. J. Cancer 143 (9): 2092–2104. | Volonte, D. et al. (2020) Caveolin-1, a master regulator of cellular senescence. Cancer Metastasis Rev. 39 (2): 397–414.
    相关实验
    • T-cell dependent antigen specific in situ staining (Pe)

      -conjugated secondary Ab choice: 10- add the biotin-conjugated goat anti-rabbit (50 to 100 µl, dilution 1:200) and incubate for 30 min. 11- wash thrice in TBS-T. From this step on follow either "Development (Avidin-HRP) " or "Double staining

    • Anti-GFP/BrdU In Situ Immunostaining

      Dilute 1 µL fresh streptavidin-Alexa Flour 555 in 1 mL PBS (1:1,000).  Spin the dilute antibody at high speed for 30'  to remove particulates.  Add supernatant to specimen and incubate 30' at room temp.  Remove antibody and add 1 mL PBS.  O.K

    • ELISA Procedure for Measuring Serum Antibody Titer

      . 2. Prepare buffer solutions. 3. Prepare a solution of the peptide, protein or peptide/conjugate (10 µg/mL with respect to the peptide or protein) in sodium carbonate buffer. 4. Pipette 200 µL of either peptide, peptide carrier conjugate, or sodium carbonate

    图标技术资料

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    文献支持
    Caveolin-1 Antibody, anti-human, PE, REAdye_lease™, 200 µL
    询价