- 询价
- Miltenyi Biotec
- 德国
- 130-122-724
- 2025年12月09日
- Flow cytometry
- cell line
- human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD94
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL287
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD94 Antibody, anti-human, REAlease®
- 抗体名：
CD94 Antibody, anti-human, REAlease®
- 规格：
100 tests
Identification and enumeration of CD94+ cells by flow cytometryClone REAL287 is an antibody fragment derived from the full CD94 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL287 recognizes CD94, an approximately 45 kDa, single-pass, type II transmembrane protein, which belongs to C-type lectin superfamily. CD94 associates covalently with NKG2 family members and forms disulfide bonded heterodimers. CD94-NKG2 receptors bind HLA-E, the non-classical MHC class Ib molecule. Depending on the associated NKG2 member, CD94-NKG2 heterodimer transmits either activating or inhibitory signal. For, e.g, via immunoreceptor tyrosine based-inhibitory motifs (ITIMs) containing NKG2A, CD94-NKG2A heterodimers inhibit NK cell cytotoxicity. Besides NK cells, expression of CD94-NKG2 heterodimers is also shown on NK-T cells and a small percentage of CD8 cells in mice, where the crosslinking of CD94-NKG2 was shown to reduce the level of spontaneous apoptosis. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Brooks, A. G. et al. (1997) NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J. Exp. Med. 185: 795–800. | Braud, V. M. et al. (1998) HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391 (6669): 795–799. | Gunturi, A. et al. (2003) Preferential survival of CD8 T and NK cells expressing high levels of CD94. J Immunol 170: 1737–1745. | Wolpert, F. et al. (2015) Interferon-β modulates the innate immune response against glioblastoma initiating cells. PLoS One 10 (10): e0139603. | Canté-Barrett, K. et al. (2017) Loss of CD44dim expression from early progenitor cells marks T-cell lineage commitment in the human thymus. Front Immunol 8: 32.
技术资料暂无技术资料 索取技术资料
文献支持
CD94 Antibody Kit, anti-human, FITC, REAlease®, 100 tests
询价
