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- 详细信息
- 技术资料
- 免疫原:
Notch2
- 亚型:
hamster IgG
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
HMN2-35
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
hamster
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 靶点:
Notch2
- 抗体英文名:
Notch2 Antibody, anti-mouse
- 抗体名:
Notch2 Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Identification and enumeration of Notch2+ cells by flow cytometryClone HMN2-35 recognizes Notch2, a member of the Notch receptor family. Notch2 acts as a receptor for the membrane bound ligands Jagged1, Jagged2 and Delta1. Notch signaling pathway is evolutionary conserved in the animal kingdom, where Notch receptors upon ligand binding undergo two proteolytic cleavages. The second cleavage releases the Notch intracellular domain (NICD), which translocates into the nucleus, forms an activator complex with the DNA binding protein RBP-J and activates genes of the enhancer of split locus. Notch signaling network regulates a number of biological processes involved in determination of cell fate, cell differentiation and apoptosis etc.
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Notch2 Antibody, anti-mouse, APC, 30 µg in 1 mL
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