CD34 Antibody, anti-human, PE,

Identification and enumeration of CD34+ cells by flow cytometryClone REAL1456 is an antibody fragment derived from the full CD34 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL1456 recognizes the human CD34 antigen, a single chain transmembrane glycoprotein, expressed on human hematopoietic stem and progenitor cells, endothelial progenitor cells, vascular endothelial cells, embryonic fibroblasts, and some cells in fetal and adult nervous tissue. The antigen is absent on fully differentiated hematopoietic cells such as normal peripheral blood lymphocytes, monocytes, granulocytes, erythrocytes, and platelets. CD34 antibodies can be used for studies of hematopoiesis and nonhematopoiectic stem cells, phenotyping of endothelial cells, and endothelial progenitor cells (EPCs), hematopoietic stem cells, and studies on phenotyping of hematologic malignancies, e.g. the identification of blasts in leukemia. Additionally it is a marker for solitary fibrous tumors and gastrointestinal stromal tumors. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |