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Granzyme A Antibody, anti-huma

n, PE, REAfinity™, 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-137-292
  • 2025年12月09日
  • MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • human cell line
  • human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Granzyme A

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA1420

    • 标记物

      PE

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      human cell line

    • 应用范围

      MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 抗体英文名

      Granzyme A Antibody, anti-human, REAfinity™

    • 抗体名

      Granzyme A Antibody, anti-human, REAfinity™

    • 规格

      200 µL

    Recombinant antibody for detection of Granzyme A+ cellsClone REA1420 recognizes Granzyme A, a member of serine protease family expressed exclusively by cytotoxic T lymphocytes and natural killer (NK) cells. Granzyme A is a homodimeric protease and is one of the five granzymes expressed by humans. Also known as granule enzymes, granzymes comprise majority of the mass of cytolytic granules in cytotoxic T lymphocytes (CTLs) and NK cells. NK cells and γδ T cells express granzymes constitutively, whereas expression in T lymphocytes is stimulation dependent. Main function attributed to granzymes is to indue apoptotic death of infected and transformed cells. Granzymes other than granzyme B, exert relatively weaker apoptotic activity. Additional reported functions of granzyme A include, to facilitate the migration of T and NK cells and induction of cytokine secretion. |

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    图标文献和实验
    该产品被引用文献
    Müllbacher, A. et al. (1999) Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc. Natl. Acad. Sci. U.S.A. 96 (13): 13950 –13955. | Trapani, J. A. (2001) Granzymes: a family of lymphocyte granule serine proteases. Genome Biol. 2 (12): 3014.1–3014.7. | Grossman, W. J. et al. (2004) Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 104: 2840–2848.
    相关实验
    • T-cell dependent antigen specific in situ staining (Pe)

      -conjugated secondary Ab choice: 10- add the biotin-conjugated goat anti-rabbit (50 to 100 µl, dilution 1:200) and incubate for 30 min. 11- wash thrice in TBS-T. From this step on follow either "Development (Avidin-HRP) " or "Double staining

    • AbC Anti-Mouse Bead Kit

      suspension. 5)        Label another sample tube for each fluorochrome-conjugated antibody you are using, and add 1 drop of AbC capture beads (Component A in the AbC Anti-Mouse Bead Kit) to each tube. 6)        Add a pre-titrated

    • AbC Anti-Rat/Hamster Bead Kit

      1 μL   5)      Label another sample tube for each fluorochrome-conjugated antibody you are using, and add 1 drop of AbC capture beads (Component A in the AbC Anti-Mouse Bead Kit) to each tube. 6)     

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    文献支持
    Granzyme A Antibody, anti-human, PE, REAfinity™, 200 µL
    询价