EZH2 Antibody, anti-human/mous

Identification and enumeration of EZH2+ cells by flow cytometryClone REA907 recognizes the human and mouse EZH2 protein, a methyltransferase which plays an essential role in the regulation of homeobox gene expression. EZH2, also known as enhancer of zeste homolog 2, belongs to the polycomp group (PcG). Members of this family play an essential role in stem-cell identity as well as cellular differentiation during development via transcriptional repression and disease. EZH2, first described in drosophila, is found in higher levels in different kind of tumor cells, and it is also expressed in thymocytes, and, depending on their stage, subsets of T cells and B cells. | Additional information: Clone REA907 displays negligible binding to Fc receptors.