- 询价
- Miltenyi Biotec
- 德国
- 130-111-633
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD8b
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA793
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD8b Antibody, anti-mouse, REAfinity™
- 抗体名：
CD8b Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD8b+ cells by flow cytometryClone REA793 recognizes both alloantigeneic forms of the mouse CD8b antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3 or Lyt-3). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8aa homodimer or as a CD8ab heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8+ lymphocyte subsets. The CD8ab heterodimer is expressed on cytotoxic T cells and thymocytes. | Additional information: Clone REA793 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Nakayama, K. et al. (1989) Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments. J Immunol 142 (7): 2540–2546. | Blanc, D. et al. (1998) Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants. Eur. J. Immunol. 18 (4): 613–619. | Chang, H. C. et al. (2005) Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer. Immunity 23 (6): 661–671.
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CD8b Antibody, anti-mouse, PE, REAfinity™, 150 µg in 1 mL
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