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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD72
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA231
- 标记物:
APC-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:11
- 抗体英文名:
CD72 Antibody, anti-human, REAfinity™
- 抗体名:
CD72 Antibody, anti-human, REAfinity™
- 规格:
30 tests in 300 µL
Identification and enumeration of CD72+ cells by flow cytometryClone REA231 recognizes CD72, a 45 kDa type II membrane protein with a C-type lectin-like domain. Expression of CD72 is found on most B-lineage cells, follicular dendritic cells, mast cells, and liver Kupffer cells. CD72 is recognized as negative regulator of B cell receptor (BCR) signaling, as well as regulating mast cell growth and differentiation via KIT activation. The inhibitory role of CD72 is exerted via the ITIM sequence in the cytoplasmic tail. | Additional information: Clone REA231 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Kataoka, T. R. et al. (2010) CD72 negatively regulates KIT-mediated responses in human mast cells. J Immunol 184: 2468–2475. | Li, D. H. et al. (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J Immunol 176: 5321–5328.
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CD72 Antibody, anti-human, APC-Vio® 770, REAfinity™, 30 tests in 300 µL
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