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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD3ε (intracellular)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA975
- 标记物:
Vio R667
- 适应物种:
human, mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD3ε (intracellular) Antibody, anti-human/mouse, REAfinity™
- 抗体名:
CD3ε (intracellular) Antibody, anti-human/mouse, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD3ε (intracellular)+ cells by flow cytometryClone REA975 recognizes an intracellular part of the CD3ε chain (activation epitope). CD3ε is a single-pass type I membrane protein, which is a part of the CD3 complex and a subunit of the TCR complex. The CD3 complex mediates signal transduction in several intracellular pathways and has a role in T cell activation and antigen recognition by binding the peptide/MHC antigen complex. CD3ε is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes. | Additional information: Clone REA975 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Gold, D. P. et al. (1987) Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family. Proc. Natl. Acad. Sci. U.S.A. 84 (21): 7649–7653. | Clevers, H. et al. (1988) Characterization and expression of the murine CD3-epsilon gene. Proc. Natl. Acad. Sci. U.S.A. 85 (22): 8623–8627. | Soudais, C. et al. (1993) Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency. Nat. Genet. 3 (1): 77–81.
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CD3ε (intracellular) Antibody, anti-human/mouse, Vio® R667, REAfinity™, 30 tests in 60 µL
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