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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD49a
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1106
- 标记物:
PE-Vio 615
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
CD49a Antibody, anti-human, REAfinity™
- 抗体名:
CD49a Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD49a+ cells by flow cytometryClone REA1106 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin α1, interacts with integrin β1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin α1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells. | Additional information: Clone REA1106 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Hemler, M. E. et al. (1985) Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells. J. Biol. Chem. 260: 15246–15252. | Miettinen, M. et al. (1993) Distribution of VLA integrins in solid tumors. Emergence of tumor-type-related expression. Patterns in carcinomas and sarcomas. Am. J. Pathol. 142 (4): 1009–1018. | Boiret, N. et al. (2005) Characterization of nonexpanded mesenchymal progenitor cells from normal adult human bone marrow. Exp. Hematol. 33 (2): 219–225.
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CD49a Antibody, anti-human, PE-Vio® 615, REAfinity™, 100 tests in 200 µL
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