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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD35
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1133
- 标记物:
APC-Vio 770
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD35 Antibody, anti-human, REAfinity™
- 抗体名:
CD35 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD35+ cells by flow cytometryClone REA1133 recognizes the human cell surface protein CD35, the C3b/C4b receptor, also known as CR1 or complement receptor type I. Four CD35 allotypes with different molecular weights are known; 190, 220, 250, and 280 kDa. CD35 is expressed on hematopoietic cells such as granulocytes, monocytes, B cells, subsets of NK and T cells, erythrocytes, and follicular dendritic cells (DCs). Known functions of CD35 include transport of C3 complexes on erythrocytes, complement activation, phagocytosis, and inhibition of the activation-induced proliferation of T and B cells. | Additional information: Clone REA1133 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Reynes, M. et al. (1985) Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens. J Immunol 135: 2687–2694. | Klickstein, L. B. et al. (1988) Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis. J. Exp. Med. 168: 1699–1717. | Reilly, B. et al. (2010) Human peripheral CD4+ T-cells expressing complement receptor 1 (CR1, CD35). J Immunol 184 (1 Supplement): 138.3.
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CD35 Antibody, anti-human, APC-Vio® 770, REAfinity™, 100 tests in 200 µL
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