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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD70
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA292
- 标记物:
Vio Bright B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD70 Antibody, anti-human, REAfinity™
- 抗体名:
CD70 Antibody, anti-human, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of CD70+ cells by flow cytometryClone REA292 recognizes the human CD70 antigen, a 50 kDa type II transmembrane glycoprotein also known as CD27 ligand (CD27L) or tumor necrosis factor ligand superfamily member 7 (TNFSF7). CD70 is a member of the TNF superfamily and is expressed by activated mouse T, B, and NK lymphocytes, activated plasmacytoid dendritic cells (pDCs), chronic B cell lymphocytic leukemia, and large B cell lymphomas. It interacts with CD27, its ligand on T cells, in order to promote T-B cell cross-stimulation and co-stimulates B cell proliferation and immunoglobulin production. It also plays a role in the pDC-induced B cell differentiation. | Additional information: Clone REA292 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Bowman, M. R. et al. (1994) The cloning of CD70 and its identification as the ligand for CD27. J Immunol 152 (4): 1756–1761. | Goodwin, R. G. et al. (1993) Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Cell 73 (3): 447–456.
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CD70 Antibody, anti-human, Vio® Bright B515, REAfinity™, 100 tests in 200 µL
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