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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD262
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA1233
- 标记物:
PE
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD262 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD262 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD262+ cells by flow cytometryClone REA1233 recognizes the murine CD262 antigen, a protein of the TNF-receptor superfamily, expressed on leukocytes, placenta cells, liver cells and some tumor cells and tumor cell lines (such as NIH-3T3). CD262 is also known as Death receptor 5 (DR5), TRAIL-R2, and TNFRSF10B. CD262 is a receptor for TRAIL, its binding induces apoptosis by activating the NF-κB pathway. | Additional information: Clone REA1233 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Hayakawa, Y. et al. (2004) NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 172 (1): 123–129. | Sato, K. et al. (2005) TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse. J Immunol (174): 4025–4033. | Takeda, K. et al. (2004) Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy. J. Exp. Med. 4 (199): 437–448. | Grisendi, G. et al. (2010) Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy. Cancer Res. 70 (9): 3718–3729. | Shanker, A. et al. (2008) Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody. J. Natl. Cancer Inst. 100 (9): 649–662. | Iannello, A. et al. (2009) Potential role of interleukin-18 in the immunopathogenesis of AIDS: involvement in fratricidal killing of NK cells. J. Virol. 83 (12): 5999–6010.
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CD262 Antibody, anti-mouse, PE, REAfinity™, 30 µg in 200 µL
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