- 询价
- Miltenyi Biotec
- 德国
- 130-102-767
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD229 (Ly-9)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA273
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
CD229 (Ly-9) Antibody, anti-mouse, REAfinity™
- 抗体名：
CD229 (Ly-9) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD229 (Ly-9)+ cells by flow cytometryClone REA273 recognizes both mouse CD229 antigen alleles, Ly9.1 and Ly9.2. CD229 is a glycoprotein of the SLAM family also known as Ly9 or SLAMF3 which is a homophilic cell surface receptor present on a variety of immune cell types including T cells, B cells, NK cells, and thymocytes. It has been shown to interact with the adaptor proteins, SLAM-associated protein and EAT-2. CD229 is highly expressed on innate-like lymphocytes such as iNKT cells and in contrast to SLAMF1 and SLAMF6, CD229 plays a negative rather than a positive role in the signaling pathways required for innate-like lymphocyte development in the thymus. | Additional Information: Clone REA273 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J Immunol 174 (11): 7033–7042. | Sintes, J. et al. (2013) Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells. J Immunol 190: 21–26. | Tovar, V. et al. (2000) Gene structure of the mouse leukocyte cell surface molecule Ly9. Immunogenetics 51 (10): 788–793.
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CD229 (Ly-9) Antibody, anti-mouse, PE, REAfinity™, 30 µg in 1 mL
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