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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD200R3
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA128
- 标记物:
Biotin
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD200R3 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD200R3 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 1 mL
Identification and enumeration of CD200R3+ cells by flow cytometryClone REA128 recognizes the human CD200R3 antigen. CD200R is an approximately 33 kDa single-pass type I membrane-protein which is a disulfide-linked dimer on the cell surface. It is reported, that the four different isoforms of CD200R (CD200R1, CD200R2, CD200R3, CD200R4) bind to CD200 (OX-2) as ligand. CD200 is primarily expressed on myeloid cells but also expressed on T and B lymphocytes. The combination of CD200R and CD200 inhibits mast cell degranulation, promotes macrophage activation, and decreases the activation of lymphocytes. | Additional information: Clone REA128 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Gorczynski, R. et al. (2004) CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J Immunol 172: 7744–7749. | Wright, G. J. et al. (2003) Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol 171: 3034–3046. | Rijkers, E. S. et al. (2008) The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes. Mol. Immunol. 45 (4): 1126–1135.
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CD200R3 Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 1 mL
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