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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD202b (TIE-2)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA735
- 标记物:
Vio Bright FITC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD202b (TIE-2) Antibody, anti-mouse, REAfinity™
- 抗体名:
CD202b (TIE-2) Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD202b (TIE-2)+ cells by flow cytometryClone REA735 recognizes the CD202b antigen, also known as TIE-2 or TEK. CD202b is a tyrosine-protein kinase which is mainly expressed in endothelial cells and their progenitors. CD202b is a cell-surface receptor for angiopoietins and is involved in angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, and re-organization of the actin cytoskeleton. | Additional information: Clone REA735 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Dumont, D. J. et al. (1993) The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 8 (5): 1293–1301. | Jones, N. et al. (1999) Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J. Biol. Chem. 274 (43): 30896–30905. | Fiedler, U. et al. (2003) Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. J. Biol. Chem. 278 (3): 1721–1727.
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CD202b (TIE-2) Antibody, anti-mouse, Vio® Bright FITC, REAfinity™, 30 µg in 200 µL
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