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- 详细信息
- 技术资料
- 免疫原:
CD267 (TACI)
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
8F10
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 靶点:
CD267 (TACI)
- 抗体英文名:
CD267 (TACI) Antibody, anti-mouse
- 抗体名:
CD267 (TACI) Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Identification and enumeration of CD267 (TACI)+ cells by flow cytometryClone 8F10 recognizes CD267, a type III transmembrane protein receptor that binds to APRIL and BAFF and also interacts with heparan sulfate proteoglycans (HSPGs). Expression of CD267 is found on subset of T cells, marzinal zone (MZ) and, B1 B cells. A dual role of TACI has been suggested in regulating B cell activation. TACI-/- mice have high number of hyper-reactive B cells, indicating an inhibitory role of TACI. On the other hand, mice lacking TACI are unable to mount normal T-cell independent type 2 (TI-2) immune response and thus suggesting a positive role in promoting B cell activation.
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CD267 (TACI) Antibody, anti-mouse, APC, 30 µg in 1 mL
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