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CD177 Antibody, anti-human, Vi

o® Bright B515, REAfinity™, 30 tests in 60 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-133-063
  • 2025年12月09日
  • Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
  • human cell line
  • human, non-human primate
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德国美天旎生物技术有限公司
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      CD177

    • 亚型：

      recombinant human IgG1

    • 形态：

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件：

      避光，4-8℃

    • 克隆性：

      REA258

    • 标记物：

      Vio Bright B515

    • 适应物种：

      human, non-human primate

    • 保质期：

      24个月

    • 供应商：

      Miltenyi Biotec

    • 宿主：

      human cell line

    • 应用范围：

      Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry

    • 浓度：

      1:50

    • 抗体英文名：

      CD177 Antibody, anti-human, REAfinity™

    • 抗体名：

      CD177 Antibody, anti-human, REAfinity™

    • 规格：

      30 tests in 60 µL

    Identification and enumeration of CD177+ cells by flow cytometryClone REA258 recognizes CD177, which is also known as neutrophil specific antigen 1. CD177, a member of the µPAR family, is a 58–64 kDa glycosylphosphatidylinositol-anchored glycoprotein expressed exclusively by subset of neutrophils, neutrophilic metamyelocytes, and myelocytes and is suggested to play a role in neutrophil mediated immune reponse as evident by its up-regulation on neutrophils in a number of inflammatory settings such as bacterial infection. Furthermore, CD177 can directly bind to PECAM-1 allowing neutrophil-endothelial cell interactions and thus contributing to neutrophil transmigration. Overexpression of CD177 is also seen in patients with polycythemia vera, making it a useful diagnostic marker. | Additional information: Clone REA258 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Sachs, U. J. H. et al. (2007) The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31). J. Biol. Chem. 282: 23603 –23612. | Monti, M. et al. (2017) Integrin-dependent cell adhesion to neutrophil extracellular traps through engagement of fibronectin in neutrophil-like cells. PLoS One 12 (2): . | Beyrau, M. et al. (2012) Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity. Open Bio 2: 120134. | Wu, Z. et al. (2016) Heterogeneity of human neutrophil CD177 expression results from CD177P1 pseudogene conversion. PLoS Genet. 12 (5): . | Tackeray, J. T. et al. (2016) Targeting amino acid metabolism for molecular imaging of inflammation early after myocardial infarction. Theranostics 6 (11): 1768–1779.
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    • AbC Anti-Rat/Hamster Bead Kit

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    • AbC Anti-Mouse Bead Kit

      实验步骤   1.  Using the AbC™ Anti-Mouse Bead Kit 1)        Completely resuspend the AbC™ capture beads (Component A) and negative beads (Component B) by gently vortexing for 30 seconds before use. 2)        Label

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    CD177 Antibody, anti-human, Vio® Bright B515, REAfinity™, 30 tests in 60 µL
    询价