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MHC Class II (I-Ak) Antibody,

anti-mouse, Vio® Bright FITC, REAfinity™, 30 µg in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-109-276
  • 2025年12月09日
  • Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • human cell line
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      MHC Class II (I-Ak)

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      REA610

    • 标记物

      Vio Bright FITC

    • 适应物种

      mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 浓度

      1:10

    • 抗体英文名

      MHC Class II (I-Ak) Antibody, anti-mouse, REAfinity™

    • 抗体名

      MHC Class II (I-Ak) Antibody, anti-mouse, REAfinity™

    • 规格

      30 µg in 1 mL

    Identification and enumeration of MHC class II (I-Ak)+ cells by flow cytometryClone REA610 recognizes the β chain of the mouse MHC class II alloantigen I-Ak of H-2k bearing mouse strains. It also cross-reacts with the H-2f, H-2r, and H-2s haplotypes, but reactivity to other haplotypes (i.e., b, d, p, and q) has not been observed. It also cross-reacts with splenocytes from nonobese diabetic (NOD) mice, and with lymph node cells of BN, DA, WRA, and WRC rats. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes, macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow. | Additional information: Clone REA610 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Bhattacharya, A. et al. (1981) A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J Immunol 127 (6): 2488–2495. | Nelson, C. A. et al. (1996) A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak. J Immunol 157 (2): 755–762. | Ting, J. P. et al. (2002) Genetic control of MHC class II expression. Cell 109: 21–33.
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    文献支持
    MHC Class II (I-Ak) Antibody, anti-mouse, Vio® Bright FITC, REAfinity™, 30 µg in 1 mL
    询价