- 询价
- Miltenyi Biotec
- 德国
- 130-116-812
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human, non-human primate
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD152
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA1003
- 标记物：
Vio R667
- 适应物种：
human, non-human primate
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD152 Antibody, anti-human, REAfinity™
- 抗体名：
CD152 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD152+ cells by flow cytometryClone REA1003 recognizes the human CD152, an integral membrane protein of the immunoglobin superfamily which is also called CTLA-4. CD152 is a negative regulator of T cell activation. It is transiently expressed on activated CD28+ T cells and is a ligand for CD80 and CD86. CD4+FoxP3+ regulatory T cells are reported to constitutively express CD152. CD152 may also be detected on B cells when cultured with activated T cells. | Additional information: Clone REA1003 displays negligible binding to Fc receptor.
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文献和实验该产品被引用文献
Kuiper, H. M. et al. (1995) Activated T cells can induce high levels of CTLA-4 expression on B cells. J Immunol 155 (4): 1776–1783. | Castan, J. et al. (1997) Accumulation of CTLA-4 expressing T lymphocytes in the germinal centres of human lymphoid tissues. Immunology 90 (2): 265–271. | Schlotmann, T. et al. (2000) CD alphabeta T lymphocytes express high levels of the T lymphocyte antigen CTLA-4 (CD152) in acute malaria. J. Infect. Dis. 182 (1): 367–370. | Sansom, D. M. and Walker, L. S. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol. Rev. 212: 131–148.
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CD152 Antibody, anti-human, Vio® R667, REAfinity™, 100 tests in 200 µL
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