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- 详细信息
- 技术资料
- 保存条件:
<p>12 months from date of receipt / reconstitution, 2 to 8 °C as supplied</p>
- 供应商:
斯达特
- 规格:
25μl/100μl
| 规格: | 25μl | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2100.0 |
CD152, also known as CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), is a protein receptor that functions as an immune checkpoint. It is a member of the immunoglobulin superfamily and is expressed on the surface of T cells. The CD152 gene consists of 4 exons and encodes a protein with a signal peptide, an Ig-like domain, a transmembrane region, and a cytoplasmic domain. CD152 plays an essential role in regulating T cell activation by binding to its ligands CD80 and CD86, which are expressed on antigen-presenting cells. This binding can inhibit the over-activation of T cells, thus maintaining immune homeostasis.
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