- 询价
- Miltenyi Biotec
- 德国
- 130-110-703
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD11c
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA754
- 标记物：
PE-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD11c Antibody, anti-mouse, REAfinity™
- 抗体名：
CD11c Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD11c+ cells by flow cytometryClone REA754 recognizes the mouse CD11c antigen, also known as integrin αX or Itgax. CD11c is present in dendritic cells in lymphoid organs and blood, in Langerhans cells in the epidermis, in dendritic cell progenitors in the bone marrow, and in in vitro–generated bone marrow–derived dendritic cells. In spleen and lymph node, CD11c is found at high levels on conventional CD11c+CD45R–mPDCA-1– dendritic cells, and at moderate levels on CD11c+CD45R+mPDCA-1+ plasmacytoid dendritic cells. CD11c is reported to be weakly expressed on NK cells, B cells, and T cell subsets. About 1–3% of splenocytes, 2% of bone marrow cells, as well as <1% of lymph node cells and thymocytes express CD11c. CD11c is a receptor for fibrinogen. It mediates cell-cell interaction during inflammatory responses and is involved in monocyte adhesion and chemotaxis. | Additional information: Clone REA754 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (2): 301–314. | López-Rodríguez, C. et al. (1996) AP-1 regulates the basal and developmentally induced transcription of the CD11c leukocyte integrin gene. J Immunol 156 (10): 3780–3787.
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文献支持
CD11c Antibody, anti-mouse, PE-Vio® 770, REAfinity™, 150 µg in 1 mL
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