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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD11b
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA592
- 标记物:
PE-Vio 615
- 适应物种:
human, mouse, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD11b Antibody, anti-mouse, REAfinity™
- 抗体名:
CD11b Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD11b+ cells by flow cytometryClone REA592 recognizes the mouse CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. CD11b is expressed on monocytes, macrophages, and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5+ B-1 cells, and subsets of dendritic cells. Clone REA592 recognizes also the non-human primate and human CD11b antigen. | Additional information: Clone REA592 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Pahl, H. L. et al. (1992) Characterization of the myeloid-specific CD11b promoter. Blood 79 (4): 865–870. | Lebson, L. et al. (2010) Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. J. Neurosci. 30 (29): 9651–9658. | Liu, T. et al. (2014) Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation. Sci Rep 4: 4833.
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CD11b Antibody, anti-mouse, PE-Vio® 615, REAfinity™, 30 µg in 200 µL
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