- 询价
- Miltenyi Biotec
- 德国
- 130-111-609
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD103
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA789
- 标记物：
Vio Bright B515
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
CD103 Antibody, anti-mouse, REAfinity™
- 抗体名：
CD103 Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of CD103+ cells by flow cytometryClone REA789 recognizes the mouse CD103 antigen, a 175 kDa large, type I transmembrane glycoprotein also known as αE integrin. CD103 associates non-covalently with integrin β7 thereby forming the heterodimeric integrin αEβ7. It mediates cell-cell contact and is involved in homing processes by binding to its ligand e-cadherin. CD103 is expressed on >90% of intestinal intraepithelial lymphocytes (IEL), epithelial T cells, and regulatory T cells. Due to its differential expression on dendritic cells from peripheral tissues, it is useful in identifying dendritic cell subsets from intestinal lamina propria, lung, and dermis. | Additional information: Clone REA789 displays negligible binding to Fc receptors
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文献和实验该产品被引用文献
Sung, S. S. et al. (2006) A major lung CD103 alphaE-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J Immunol 176 (9): 2161–2172. | Bogunovic, M. et al. (2009) Origin of the lamina propria dendritic cell network. Immunity 31 (3): 513–525. | Ginhoux, F. et al. (2007) Blood-derived dermal Langerin+ dendritic cells survey the skin in the steady state. J. Exp. Med. 204 (13): 3133–3146.
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CD103 Antibody, anti-mouse, Vio® Bright B515, REAfinity™, 150 µg in 1 mL
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